BoneStrength is a Silico Trial solution aimed at assessing the efficacy of antiresorptive drugs, a class of drugs aimed at treating osteoporosis and preventing fragility bone fractures. 

At the core of the BoneStrength there is Biomechanical Computed Tomography (BCT), a Digital Twin pipeline that allows patient-specific femur fracture risk estimation starting from a femur CT scan and a few other personal data (such as height and weight). 

Our aim is to simulate a phase III clinical trial by creating a large number of virtual patients (~1000), estimating their bone ageing with and without pharmacological treatments over several years, and evaluating patient fracture risk in the different scenarios. 

We shall then pursue regulatory qualification with EMA.