Related EU-Funded Projects

In Silico World is only one of the many projects involved in furthering the adoption of in silico technologies. Discover other EU-funded projects related to in silico medicine.

European Virtual Human Twin

EDITH is a Coordination and Support Action (CSA), funded by the European Commission, which will capitalise on the developments of digital technologies, high-performance computing, availability and access to research and healthcare data in Europe, with the mission of defining a roadmap to go from separated single organ systems, to data-driven and knowledge-driven fully integrated multiscale and multiorgan whole-body twin. EDITH will facilitate this process by building an evolutionary ecosystem, driven by a consensus among the relevant European communities, and implemented through the aid of practical tools, such as a data/model repository (within the scope of EDITH), and a simulation platform (to be implemented after EDITH).


Start date: 1 October 2022

End date: 30 September 2024

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Simulation of Cardiac Devices & Drugs for in-silico Testing and Certification

SimCardioTest aims to design new predictive tools in cardiac pathologies and aims to accelerate the uptake of computer simulations for testing medicines and medical devices. One objective is to provide a framework and wide approach of in-silico methods (computer modelling and simulation) where generic and standardized elements can be used for other applications. The second one aims to demonstrate that such approach can help develop devices and drugs as well as reduce the cost and time to market and gain the trust of scientists, companies, regulatory bodies, physicians, and patients. The final objective is to impact the whole clinical trials, since this approach can replace some invasive aspects of these trials, and maybe provide novel biomarkers for more accurate clinical trials.


Start date: 1 January 2021

End date: 31 December 2024

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SIMCor (In-Silico testing and validation of Cardiovascular IMplantable devices)

SIMCor is developing a computational platform for in-silico development, validation and regulatory approval of cardiovascular implantable devices. The project focuses on two medical devices, transcatheter aortic valve implants and pulmonary artery pressure sensors, and develops methodologies and tools for in-silico clinical trials. These include generation and validation of virtual cohorts of patients and animals, models for virtual device implantation and assessment of device safety, efficacy and usability, guidelines and standard operating procedures, and quantitative assessment of the benefits of in-silico trials on healthcare, industry, and society.


Start date: 1 January 2021

End date: 31 December 2023

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In-silico development and clinical trial platform for testing in-situ tissue engineered heart valves

SimInSitu promises the first in-silico clinical trial platform to predict the short- and long-term response of in-situ tissue engineered heart valves (TEHV) in humans. We will enable the simultaneous assessment and optimization of the performance and safety of TEHV by a multidisciplinary approach combining advanced patient-specific computational models, tissue and growth remodelling algorithms, and dedicated device models. SimInSitu will not only develop computer models but will also verify and validate them thoroughly by making use of in-vitro and in-vivo data and, where necessary, will generate new data to support the credibility of in-silico clinical trials.


Start date: 1 January 2021

End date: 31 December 2024

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