Here you can access all the publications produced as part of the In Silico World project and made publicly and freely available to the in silico medicine research community.

  • Musuamba, F.T., Skottheim Rusten, I., Lesage, R., Russo, G., Bursi,R., Emili, L., Wangorsch, G., Manolis, E., Karlsson, K.E., Kulesza, A., Courcelles, E., Boissel, J.P., Rousseau, C.F., Voisin, E.M., Alessandrello, R., Curado, N., Dall’ara, E., Rodriguez, B., Pappalardo, F., Geris, L., 2022. Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility. CPT: Pharmacometrics & Systems Pharmacology. Vol. 10., Issue 8.


  • Herpelinck, T.,  Ory, L., Nasello, G., Barzegari, M., Bolander, J., Luyten, F. P., Tylzanowski, P., Geris, L., 2022. An integrated single-cell atlas of the skeleton from development through adulthood. bioRxiv


  • Curreli, C., Di Salvatore, V., Russo, G., Pappalardo, F., Viceconti, M., 2022. A Credibility Assessment Plan for an In Silico Model that Predicts the Dose-Response Relationship of New Tuberculosis Treatments. Annals of Biomedical Engineering


  • Garavelli, G., Cristina Curreli, C., Palanca, M., Aldieri, A., Cristofolini, L., Viceconti, M., 2022. Experimental validation of a subject-specific finite element model of lumbar spine segment using digital image correlation. Plos one


  • Pappalardo, F., Wilkinson, J., Busquet, F., Bril, A., Palmer, M., Walker, B., Curreli, C., Russo, G., Marchal, T., Toschi, E., Alessandrello, R., Costignola, V., Klingmann, I., Contin, M., Staumont, B., Woiczinski, M., Kaddick, C., Di Salvatore, V., Aldieri, A., Geris, L., Viceconti M., 2022. Toward a Regulatory Pathway for the Use of in Silico Trials in The Ce Marking of Medical Devices. IEEE Journal of Biomedical and Health Informatics.

DOI: 10.1109/JBHI.2022.3198145


  • La Mattina, A.A., Baruffaldi, F., Taylor, M., Viceconti, M., 2022. Statistical Properties of a Virtual Cohort for In Silico Trials Generated with a Statistical Anatomy Atlas. Ann Biomed Eng.


  • Viceconti, M., Emili, L., Afshari, P., Courcelles, E., Curreli, C., Famaey, N., Geris, L., Horner, M., Jori, M.C., Kulesza, A., Loewe, A., Neidlin, M., Reiterer, M., Rousseau, C.F., Russo, G., Sonntag, S.J., Voisin, E.M., Pappalardo, F., 2021. Possible Contexts of Use for In Silico Trials Methodologies: A Consensus-Based Review. IEEE Journal of Biomedical and Health Informatics, vol. 25., no. 10.


  • Viceconti, M., Curreli, C., Bottin, F., Davico, G., 2021. Effect of Suboptimal Neuromuscular Control on the Risk of Massive Wear in Total Knee Replacement. Ann Biomed Eng. no. 49.


  • Biasin, E., 2021. Why accuracy needs further exploration in data protection. European Union Digital Library.


  • Wéber, R., Gyürki, D., Paal., G., 2023. First blood: An efficient, hybrid one- and zero-dimensional, modular hemodynamic solver.